In the modern surface pre-treatment process in manufacturing, using plasma chemical theory is best way for finding economical and high quality process for production site. The plasma surface treatment system do not make critical harmful thing like as toxic or dust also it is worked with small quantity of electricity and just using normal compressed air gas. Generally, air plasma surface treatment technic is used for activation and cleaning and special polymerization coating (with precursor). With air plasma treatment process, we can make the surface at hydrophobic or hydrophilic. It had been used for mainly automotive and electronic products, and now a days its application is more widen for bio, environment, medical, etc industry. The aim of this presentation is to explain air plasma surface treatment basic theory and applicable reference in industry include R2R.